Joe was awarded the Tony and Joseph Jefferson Award for his acclaimed performance as Richard Roma in David Mamet's Pulitzer Prize-winning play Glengarry Glen Ross. Some of Joe’s film and television highlights are House of Games, Searching for BobbyFisher, Godfather III, the role of Dean Martin in The Ratpack, and the voice of Fat Tony on The Simpsons. For two seasons Joe stared with Mary Steenburgen and Amber Tamblyn in the critically acclaimed CBS drama Joan of Arcadia, winner of the 2004 People’s Choice Award for best new drama as well as picking up three Emmy nominations. In 2008 Joe reprised his Emmy nominated role of Lou Manahan opposite Debra Messing in the USA Network series The Starter Wife. Among his several projects is also his participation in the Disney/Pixar film CARS2.
In April of 2011 Joe received a star on the Hollywood Walk of Fame.
On May of 2012 Joe was appointed the National Spokesperson for The U.S. Army Museum to lead the fundraising campaign to build the long-planned National Museum of the United States Army, and on May 2015 he was the recipient of the Saint Pio Award from the Saint Pio Foundation, for his humanitarian work in support of the veterans.
Joe recently completed the feature films The Bronx Bull, Ten Cent Pistol, and Compulsion. He also has co-produced a documentary on the late science fiction icon Ray Bradbury.
Joe starred as FBI Special Agent David Rossi for thirteen seasons of the Hit CBS Drama Criminal Minds, which ended its fifteenth season run in 2020.
Actor Joe Mantegna acceptance speech as a
Honorary Advocate of the Saint Pio Foundation